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KMID : 1161420120150010078
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Journal of Medicinal Food
2012 Volume.15 No. 1 p.78 ~ p.82
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Effects of Passiflora edulis (Yellow Passion) on Serum Lipids and Oxidative Stress Status of Wistar Rats
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de Souza Maricelma da Silva Soares
Barbalho Sandra Maria
Damasceno Debora Cristina
Rudge Marilza Vieira Cunha
de Campos Kleber Eduardo
Madi Ana Carolina Goyos
Coelho Bruno Ribeiro
Oliveira Rodrigo Cesar
de Melo Rodrigo Cartaxo
Donda Vinicius Castrequini
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Abstract
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The aim of this study was to evaluate the effects of Passiflora edulis f. flavicarpa Degener (yellow passion) juice on the lipid profile and oxidative stress status of Wistar rats. Adult male Wistar rats were divided in two groups (n=8 animals per group): the control group, which received water, and the treated group, which was given P. edulis juice (1,000?mg/kg). Both groups received by gavage treatment twice a day for 28 days. The treated group showed an increased high-density lipoprotein-cholesterol level and decreased low-density lipoprotein-cholesterol and free fatty acid levels compared with the control group. Levels of triglycerides and and very low-density lipoprotein-cholesterol, superoxide dismutase activity, and total glutathione concentration were not statistically different between the two groups, but the thiobarbituric acid?reactive substances concentration (indicating lipid peroxidation) decreased in the treated group. These findings suggests that P. edulis juice in the experimental conditions used showed beneficial effects on lipid profile and improved lipid peroxidation in Wistar rats.
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KEYWORD
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cholestero, llipids, oxidative stress, Passiflora edulis, rat
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